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Plastics, dioxins and paracetamol are key players in decline in male fertility – Study

 

Plastics, dioxins and paracetamol are key players in decline in male fertility – Study

Plastics, dioxins and paracetamol are key players in decline in male fertility – Study

For the first time, a study ranks the chemicals most harmful to human sperm quality.

The fast fall in human fertility demonstrates the tight relationship between population health and environmental quality. In a study published Thursday, June 9 in the journal Environment International, British and Danish experts emphasize this once more. The authors give the first assessment of the hazards to male fertility caused by mixes of ordinary chemicals, led by Andreas Kortenkamp (Brunel University, London) and Hanne Frederiksen (Rigshospitalet, Copenhagen University Hospital).

They were able to rank the compounds most suspected of lowering sperm quality in order of their contribution to the current reduction. By far the most important are plastics. BPA and its replacements (BPS, GMP), polychlorinated dioxins and other plasticizers (phthalates), certain parabens, and paracetamol are the worst (acetaminophen). According to the researchers, the general population's median cumulative exposure level to these goods is nearly 20 times the risk threshold.

For the past 30 years, there has been a fall in male fertility. Diet, smoking, stress, exposure to some common chemicals, and other things were considered to be the reason. "Many studies have been conducted out over the world for the past thirty years to quantify the features of human sperm," said Pierre Jouannet, professor emeritus at the University of Paris-Descartes and one of the major pioneers in this field of research. "The most serious of these, notably in the most economically developed countries, demonstrate a reduction in sperm quality."

A drop of 50% to 60% in less than forty years

The figures are startling. The most thorough summary to date was published in 2017. Between 1973 and 2011, the average sperm concentration of Western men declined from 99 million to 47 million sperm per milliliter, according to research led by Shanna Swan (New York University) and published in the journal Human Reproduction Update. In fewer than forty years, this represents a drop of 50% to 60%.

Other, more recent data indicate that the problem is still very much with us. In 2019, a paper by Ashley Tiegs's team (Thomas Jefferson University, Philadelphia) published in Urology studied 120,000 American and Spanish men from couples who visited a reproductive health center. In this sample, the proportion of men with fewer than 15 million motile sperm per milliliter increased from 12.4% to 21.3% between 2002 and 2017. This is an increase of nearly 10 percentage points in 15 years within this population subgroup. Read More News

 

 

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